Best answer by shorTcircuiT
First, just to be safe, I need to mention, are you positive that the .exe file for the game is indeed safe? While it could very well be a false postive, there could something there which WSA is correctly identifying. If you are not sure, you can try taking the URL of the download and checking it at www.brightcloud.com and see what it says.
I also urge you to submit a Trouble Ticket. This is simply to help verify that the file is indeed OK, and this will allow Webroot Support to Whitelist the file so that you, and others, do not continue to be bothered by a False Positive.
OK, now if you are quite sure that the file is safe, lets try to get you fixed!
Open WSA, and click the 'gear tool' next to PC Security.
Click the Quarantine tab.
Check to see if your game .exe is listed here. If so, select it and click Restore at the bottom right.
Next, blick the Block/Allow files tab.
Is your game .exe listed here? If so, and it is marked Block, change that to Allow.
If the game .exe is not listed, click the Add File button, navigate to the hard drive location where it is installed, select it and set it for allow.
Give this a try and see if it helps. If not, let us know and we will try to go from there.